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EBNA1 Binding Protein 2 (EBNA1BP2)

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NOBP; EBP2; P40; Epstein-Barr Nuclear Antigen 1 Binding Protein 2; Nucleolar protein p40; EBNA1-binding protein 2

EBNA1 Binding Protein 2 (EBNA1BP2)
CCC Q457
HGNC 15531
MGI 1916322
PubMed 11327720
RGD 1305762
UniProt Q99848
Wiki EBNA1BP2
EBP2 is a 35-kDa protein that is conserved in a variety of organisms and is predicted to form coiled-coil interactions. The region of EBNA1 that binds EBP2 and generated internal deletion mutants of EBNA1 that are deficient in EBP2 interactions. The ability to bind EBP2 correlates with the ability of EBNA1 to support the long-term maintenance in human cells of a plasmid containing the EBV origin, oriP. An EBNA1 mutant lacking amino acids 325 to 376 was defective for EBP2 binding and long-term oriP plasmid maintenance but supported the transient replication of oriP plasmids at wild-type levels. EBNA1-EBP2 interaction is important for the stable segregation of EBV episomes during cell division but not for the replication of the episomes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EBNA1 Binding Protein 2 (EBNA1BP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EBNA1 Binding Protein 2 (EBNA1BP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EBNA1 Binding Protein 2 (EBNA1BP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EBNA1 Binding Protein 2 (EBNA1BP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for EBNA1 Binding Protein 2 (EBNA1BP2) ELISA Kit Customized Service Offer
  1. "EBP2, a human protein that interacts with sequences of the Epstein-Barr virus nuclear antigen 1 important for plasmid maintenance."J. Virol. 73:2587-2595(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of p40/Epstein-Barr virus nuclear antigen 1 binding protein 2."Biochem. Biophys. Res. Commun. 283:430-436(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and partial characterization of a Mr 40,000 nucleolar antigen associated with cell proliferation."Cancer Res. 47:1123-1129(1987) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Proteomic and targeted analytical identification of BXDC1 and EBNA1BP2 as dynamic scaffold proteins in the nucleolus."Genes Cells 14:155-166(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Nucleolar scaffold protein, WDR46, determines the granular compartmental localization of nucleolin and DDX21."Genes Cells 18:780-797(2013) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]