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Striatin 3 (STRN3)

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SG2NA; Cell Cycle S/G2 Nuclear Autoantigen; Striatin, Calmodulin Binding Protein 3

Striatin 3 (STRN3)
CCC Q470
HGNC 15720
MGI 2151064
PubMed 23678272
RGD 621827
UniProt Q13033
Wiki STRN3
Anovel nuclear protein mainly expressed in S and G2 phase cells was characterized using autoantibodies from a cancer patient. cDNA clones were isolated by immunoscreening, and sequence analysis revealed that the cDNA clones encoded a 713-amino acid residue polypeptide which is provisionally named SG2NA. In the carboxyl terminal half of SG2NA, there are 6 copies of WD-40 motifs characteristic of a large family of proteins of which the prototype is beta-transducin/enhancer of split (TLE). In addition, there are nuclear localization sequence and phosphorylation sites related to the TLE proteins. Autoantibodies occurring spontaneously in certain cancer patients have been useful reagents for identifying cellular proteins and this is the first report of a novel WD-40 protein which is the target of an autoimmune response.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Striatin 3 (STRN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Striatin 3 (STRN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Striatin 3 (STRN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Striatin 3 (STRN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Striatin 3 (STRN3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Striatin 3 (STRN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Striatin 3 (STRN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Striatin 3 (STRN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Striatin 3 (STRN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Striatin 3 (STRN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Striatin 3 (STRN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Striatin 3 (STRN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Striatin 3 (STRN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Striatin 3 (STRN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Striatin 3 (STRN3) ELISA Kit Customized Service Offer
  1. "A cell-cycle nuclear autoantigen containing WD-40 motifs expressed mainly in S and G2 phase cells."Biochem. Biophys. Res. Commun. 207:1029-1037(1995) [PubMed] [Europe PMC] [Abstract]
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  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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  13. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
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  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]