Ankyrin Repeat Domain Protein 5 (ANKRD5)
[Edit]ANKEF1; Ankyrin repeat and EF-hand domain-containing protein 1
-84478.jpg)
Of the 16 known genes mapping to the male-specific locus for total IgE on chromosome 20p12, two were of particular interest:jagged 1 precursor (JAG1) and ankyrin repeat domain protein 5 (). JAG1, an important growth factor implicated in hematopoietic stem cell self-renewal, is within 0.5 Mb of the STR demonstrating maximal linkage to total IgE. JAG1 is expressed in mature B-cells, and is a principal ligand for the NOTCH1 receptor, which (in conjunction with Delta-1) has been implicated in lymphocyte precursor stem cell differentiation into T- or B-cell lineages. ANKRD5 contains eight ankyrin repeat domains and a calcium binding EF-hand domain, and is expressed in both the bone marrow and spleen. STR strongly linked to total IgE—resides within the 30 untranslated region of ANKRD5.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ankyrin Repeat Domain Protein 5 (ANKRD5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ankyrin Repeat Domain Protein 5 (ANKRD5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ankyrin Repeat Domain Protein 5 (ANKRD5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ankyrin Repeat Domain Protein 5 (ANKRD5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ankyrin Repeat Domain Protein 5 (ANKRD5) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
- "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]