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Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1)

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TPA018; OCIA; Asrij; Ovarian carcinoma immunoreactive antigen

Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1)
CCC Q498
HGNC 16074
MGI 1915345
PubMed 18328549
RGD 1359549
UniProt Q9NX40
OCIAD1 over-expression in HEY ovarian cancer cells increased LPA-induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin 10/11. OCIAD1 does not use PKC and PI3K signaling pathways to exert its effect on adhesion. In addition, LPA induced cell adhesion to collagen I was unaffected by paclitaxel (5 microM) in OCIAD1 overexpressing cells. OCIAD1 is over-expressed in metastatic ovarian cancer tissues. The effect of OCIAD1 on cell adhesion may be related to its function in ovarian cancer. Failure of paclitaxel to affect ovarian cancer cell adhesion in presence of OCIAD1 raises the possibility of OCIAD1's role in tumor metastasis. Using a mouse orthotopic LPA-dependent ovarian cancer metastasis model are focused on strategies to inhibit the potential role of OCIAD1 in tumor metastasis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Immuno Reactive Antigen Domain Containing Protein 1 (OCIAD1) ELISA Kit Customized Service Offer
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