Sideroflexin 3 (SFXN3)
Sfxn3, a member of sideroflexin family. CTPL/Sfxn3 was targeted to mitochondrial membrane like Sfxn1. The expression levels of CTPL/Sfxn3, Sfxn2, and Sfxn5 were upregulated in the early phase of differentiation into insulin-secreting cells but the expression levels of Sfxn1 and Sfxn3 did not change. All Sfxn family members were expressed in rat pancreatic islet. The expression levels of CTPL/Sfxn3, Sfxn2, and Sfxn5 were also upregulated in islets of streptozotocin-induced diabetic rats compared to normal rats. The downregulation of CTPL/Sfxn3 in a rat insulinoma cell line, INS-1, with the antisense oligonucleotide did not affect the insulin secretion. Taken together, CTPL/Sfxn3 and some other family members might be important in the differentiation of pancreatic beta-cells as a channel or a carrier molecule and be related to the regeneration of pancreatic endocrine cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ501Hu01 Recombinant Sideroflexin 3 (SFXN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Sideroflexin 3 (SFXN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sideroflexin 3 (SFXN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sideroflexin 3 (SFXN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sideroflexin 3 (SFXN3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sideroflexin 3 (SFXN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sideroflexin 3 (SFXN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sideroflexin 3 (SFXN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sideroflexin 3 (SFXN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sideroflexin 3 (SFXN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sideroflexin 3 (SFXN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sideroflexin 3 (SFXN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sideroflexin 3 (SFXN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sideroflexin 3 (SFXN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sideroflexin 3 (SFXN3) ELISA Kit Customized Service Offer
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  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]