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Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2)

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C20orf110; PINH; DOR; PIG-U; Diabetes And Obesity Regulated; Diabetes and obesity-regulated gene; p53-inducible protein U

Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2)
CCC Q503
HGNC 16104
MGI 1915978
PubMed 24713655
RGD 735085
UniProt Q8IXH6
The human gene was identified by using bioinformatic analyses which include the cDNA sequence named C20ORF110. It is composed of five exons spanning 9 kb of genomic DNA. The predicted open reading frame of TP53INP2 cDNA codes for 220 amino acids with a predicted molecular weight of 24 kDa.
TP53INP2 shows a conserved exon-intron structure with the TP53INP1ß isoform, a gene strongly activated during cellular stress by p53-mediated activation of transcription that has been assigned to human chromosome 8q22. Protein sequence comparison showed 30 and 45% of identity and similarity between the two genes, respectively. TP53INP2 is located at human chromosome 20q11.2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Protein p53 Inducible Nuclear Protein 2 (TP53INP2) ELISA Kit Customized Service Offer
  1. "Identification of a novel modulator of thyroid hormone receptor-mediated action."PLoS ONE 2:E1183-E1183(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "TP53INP2 is the new guest at the table of self-eating."Autophagy 5:383-384(2009) [PubMed] [Europe PMC] [Abstract]
  7. "The TP53INP2 protein is required for autophagy in mammalian cells."Mol. Biol. Cell 20:870-881(2009) [PubMed] [Europe PMC] [Abstract]
  8. "DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription."PLoS ONE 7:E34034-E34034(2012) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]