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Family With Sequence Similarity 8, Member A1 (FAM8A1)

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AHCP; Autosomal highly conserved protein

Family With Sequence Similarity 8, Member A1 (FAM8A1)
CCC Q528
HGNC 16372
MGI 2145496
PubMed 11707071
RGD 1307845
UniProt Q9UBU6
FAM8A1 was captured by a retrovirus, followed by multiple retrotransposition events, during primate evolution between 45 and 58 million years ago. Only the functional FAM8A1 gene is expressed and displays a ubiquitous mRNA and a testis-specific transcript present in the haploid phase of spermatogenesis.
The structural features of the FAM8A1 pseudogenes include two short sequences of similarity between the FAM8A1 mRNA and the HERV sequences at both the 5' and 3' integration sites. These hallmarks suggest an alternative model to account for the capture of FAM8A1 cellular mRNA by HERV-K, involving illegitimate recombination events at the two sites of sequence similarity during reverse transcription.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 8, Member A1 (FAM8A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 8, Member A1 (FAM8A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Family With Sequence Similarity 8, Member A1 (FAM8A1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Family With Sequence Similarity 8, Member A1 (FAM8A1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Family With Sequence Similarity 8, Member A1 (FAM8A1) ELISA Kit Customized Service Offer
  1. "Transduction of the human gene FAM8A1 by endogenous retrovirus during primate evolution."Genomics 78:38-45(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]