Periodic tryptophan protein 1 homolog is a protein encoded by the PWP1 gene.The deduced aa sequence contains 9 Trp residues, some of which are localized in repeats and that characterise the protein as a member of the WD-40 family, a group of proteins having 40-aa repeats containing Trp and Asp. The protein contains a nuclear targeting signal (KKKGK), and fractionation of transformed human amnion cells (AMA) in karyoplasts and cytoplasts confirmed that it is predominantly localized in the nucleus. Database searching indicated that IEF SSP 9502 is a putative human homologue of the Saccharomyces cerevisiae periodic Trp protein, PWP1, a polypeptide that may play a regulatory role in cell growth and/or transcription.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Periodic Tryptophan Protein 1 (PWP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Periodic Tryptophan Protein 1 (PWP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Periodic Tryptophan Protein 1 (PWP1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Periodic Tryptophan Protein 1 (PWP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Periodic Tryptophan Protein 1 (PWP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Periodic Tryptophan Protein 1 (PWP1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Periodic Tryptophan Protein 1 (PWP1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Periodic Tryptophan Protein 1 (PWP1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Periodic Tryptophan Protein 1 (PWP1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Periodic Tryptophan Protein 1 (PWP1) | ELISA Kit Customized Service Offer |
- "Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family."Gene 151:291-296(1994) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line."Electrophoresis 28:2027-2034(2007) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]