≡

CLK4 Associating Serine/Arginine Rich Protein (CLASRP)

[Edit]

SFRS16; SWAP2; CLASP; Suppressor of white-apricot homolog 2; Clk4 Associating SR-Related Protein; Splicing Factor, Arginine/Serine-Rich 16

CLK4 Associating Serine/Arginine Rich Protein (CLASRP)
CCC Q615
HGNC 17731
MGI 1855695
PubMed 15928712
RGD 1563538
UniProt Q8N2M8
Wiki CLASRP
Northern blot analysis revealed that Clasp mRNA was highly expressed in brain, and in situ hybridization of a mouse brain sagittal section hybridized with antisense probes revealed that both Clasp and Clk4 mRNAs were expressed in the hippocampus, the cerebellum, and the olfactory bulb. Two forms of Clasp were produced by a frameshift following alternative splicing. The staining of an HA-tagged short form of Clasp (ClaspS) showed a nucleoplasmic pattern, while the long form of Clasp (ClaspL) was localized as nuclear dots. In vitro protein interaction assay demonstrated that Clk4 K189R was bound to Clasp while wild Clk4 was not. Overexpression of ClaspL promoted accumulation of Clk4 K189R in the nuclear dots and the exon EB inclusion from CR-1 and CR-2 pre-mRNA of Clk1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CLK4 Associating Serine/Arginine Rich Protein (CLASRP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) CLIA Kit Customized Service Offer
n/a ELISA Kit for CLK4 Associating Serine/Arginine Rich Protein (CLASRP) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]