≡

Zinc Finger Protein 638 (ZNF638)

[Edit]

ZFML; NP220; Zinc Finger, Matrin-Like; Nuclear protein 220; Cutaneous T-cell lymphoma-associated antigen se33-1

Zinc Finger Protein 638 (ZNF638)
CCC Q631
HGNC 17894
MGI 1203484
PubMed 8647861
RGD 1309746
UniProt Q14966
Wiki ZNF638
ZNF638 is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Human NP220 binds to double-stranded DNA fragments by recognizing clusters of cytidines. Immunofluorescent microscopy with antiserum directed against NP220 revealed a punctate or "speckled" pattern and coiled body-like structures in the nucleoplasm of various human cell lines. Human NP220 shares three types of domains (MH1, MH2, and MH3) with the acidic nuclear protein, matrin 3 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 638 (ZNF638) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 638 (ZNF638) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 638 (ZNF638) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 638 (ZNF638) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 638 (ZNF638) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 638 (ZNF638) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 638 (ZNF638) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 638 (ZNF638) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 638 (ZNF638) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 638 (ZNF638) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 638 (ZNF638) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 638 (ZNF638) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 638 (ZNF638) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 638 (ZNF638) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 638 (ZNF638) ELISA Kit Customized Service Offer
  1. "A large DNA-binding nuclear protein with RNA recognition motif and serine/arginine-rich domain."J. Biol. Chem. 271:12525-12531(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Serological detection of cutaneous T-cell lymphoma-associated antigens."Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220."J. Cell. Biochem. 84:556-566(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."J. Proteome Res. 6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
  10. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  11. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  12. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  18. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]