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G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A)

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G-protein coupled receptor GPCR33

G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A)
CCC Q695
HGNC 18510
MGI 2429498
PubMed 22374969
RGD 735077
UniProt Q5T6X5
Wiki GPRC6A
Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain.
The deduced 928-amino acid protein shares 80% identity with human GPRC6A. RT-PCR detected widespread but weak expression in rat tissues, with highest expression in soft palate. Rat Gprc6a was expressed on the surface of transfected human embryonic kidney cells. Deglycosylation assays revealed that Gprc6a was highly glycosylated.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 6, Member A (GPRC6A) ELISA Kit Customized Service Offer
  1. "Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor."Gene 335:37-46(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of G protein-coupled receptor genes from the human genome sequence."FEBS Lett. 520:97-101(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids."Mol. Pharmacol. 67:589-597(2005) [PubMed] [Europe PMC] [Abstract]
  5. "GPRC6A mediates the non-genomic effects of steroids."J. Biol. Chem. 285:39953-39964(2010) [PubMed] [Europe PMC] [Abstract]