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Vacuolar Protein Sorting 54 (VPS54)

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HCC8; Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p

Vacuolar Protein Sorting 54 (VPS54)
CCC Q704
HGNC 18652
MGI 2178798
PubMed 16244655
RGD 628718
UniProt Q9P1Q0
VPS54 encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Vps54-related sequences of human, mouse, Drosophila melanogaster, Caenorhabditis elegans and Arabidopsis thaliana could be identified in the EMBL/GenBank/DDBJ database. Each of the deduced amino acid sequences of the Vps54 genes in these species contain a coiled-coil region and eight to 13 dileucine motifs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 54 (VPS54) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 54 (VPS54) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 54 (VPS54) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 54 (VPS54) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 54 (VPS54) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 54 (VPS54) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 54 (VPS54) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 54 (VPS54) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 54 (VPS54) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 54 (VPS54) ELISA Kit Customized Service Offer
  1. "Characterization of the human GARP (Golgi associated retrograde protein) complex."Exp. Cell Res. 306:24-34(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes."Mol. Biol. Cell 19:2350-2362(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex."Mol. Biol. Cell 21:3386-3395(2010) [PubMed] [Europe PMC] [Abstract]