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Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L)

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C14orf32; MISS; MAPK-Interacting And Spindle-Stabilizing Protein

Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L)
CCC Q781
HGNC 19840
MGI 2444022
PubMed 12011110
RGD 1311455
UniProt Q8NDC0
Wiki C14orf32
This protein is unstable during the first meiotic division and accumulates only in MII, where it localizes to the spindle. It is a substrate of the Mos/.../MAPK pathway. The depletion of endogenous RNA coding for this protein by three different means (antisense RNA, double-stranded [ds] RNA, or morpholino oligonucleotides) induces severe spindle defects specific to MII oocytes. Overexpressing the protein from an RNA not targeted by the morpholino rescues spindle destabilization. However, dsRNA has no effect on the first two mitotic divisions.
A new MAPK substrate involved in maintaining spindle integrity during the CSF arrest of mouse oocytes, called MISS (for MAP kinase-interacting and spindle-stabilizing protein).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase 1 Interacting Protein 1 Like Protein (MAPK1IP1L) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. , Submitted (MAY-2006) to UniProtKB
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]