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Retinol Dehydrogenase 14 (RDH14)

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PAN2; SDR7C4; Short Chain Dehydrogenase/Reductase Family 7C, Member 4; Alcohol dehydrogenase PAN2

Retinol Dehydrogenase 14 (RDH14)
CCC Q790
HGNC 19979
MGI 1920402
PubMed 12226107
RGD 1565196
UniProt Q9HBH5
Wiki RDH14
Retinoids are chromophores involved in vision, transcriptional regulation, and cellular differentiation. Members of the short chain alcohol dehydrogenase/reductase superfamily catalyze the transformation of retinol to retinal. RDH11-14 could be involved in the first step of all-trans- and 9-cis-retinoic acid production in many tissues. RDH11-14 fill the gapof 11-cis-retinal and all-trans-retinal transformations in photoreceptor (RDH12) and retinal pigment epithelial cells (RDH11).
RDH14 transcripts were localized to the photoreceptor IS. RDH14 activity was found to be similar to that of RDH11 and RDH12, acting in an oxidative and reductive capacity, depending on the cofactor available (NADP+ or NADPH, respectively).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 14 (RDH14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 14 (RDH14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 14 (RDH14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 14 (RDH14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 14 (RDH14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 14 (RDH14) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 14 (RDH14) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 14 (RDH14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 14 (RDH14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 14 (RDH14) ELISA Kit Customized Service Offer
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  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina."J. Biol. Chem. 277:45537-45546(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]