Ubiquitin Specific Peptidase 50 (USP50)
[Edit]Inactive ubiquitin carboxyl-terminal hydrolase 50; Inactive ubiquitin-specific peptidase 50
-84804.jpg)
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. is a 339 amino acid protein that belongs to the peptidase C19 family of proteins. Weakly expressed in a few tissues, USP50 contains all of the active residues necessary to function as a deubiquitinating enzyme, but it appears to be catalytically inactive. The gene ecoding USP50 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ubiquitin Specific Peptidase 50 (USP50) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ubiquitin Specific Peptidase 50 (USP50) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ubiquitin Specific Peptidase 50 (USP50) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ubiquitin Specific Peptidase 50 (USP50) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ubiquitin Specific Peptidase 50 (USP50) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ubiquitin Specific Peptidase 50 (USP50) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ubiquitin Specific Peptidase 50 (USP50) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ubiquitin Specific Peptidase 50 (USP50) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ubiquitin Specific Peptidase 50 (USP50) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ubiquitin Specific Peptidase 50 (USP50) | ELISA Kit Customized Service Offer |
- "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases."Biochem. Biophys. Res. Commun. 314:54-62(2004) [PubMed] [Europe PMC] [Abstract]
- "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
- "A genomic analysis of rat proteases and protease inhibitors."Genome Res. 14:609-622(2004) [PubMed] [Europe PMC] [Abstract]