≡

Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15)

[Edit]

Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15)
CCC Q901
HGNC 20997
MGI 3603821
PubMed 20675388
RGD 1309845
UniProt Q9H091
Spermatogenesis is a complex process through which male germ line stem cells undergo a multi-step differentiation program and sequentially become spermatogonia, spermatocytes, spermatids, and eventually spermatozoa.
ZMYND15 acts as a histone deacetylase-dependent transcriptional repressor and controls normal temporal expression of haploid cell genes during spermiogenesis. Inactivation of Zmynd15 results in early activation of transcription of numerous important haploid genes including Prm1, Tnp1, Spem1, and Catpser3; depletion of late spermatids; and male infertility. ZMYND15 represents the first transcriptional repressor identified to be essential for sperm production and male fertility.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger, MYND-Type Containing Protein 15 (ZMYND15) ELISA Kit Customized Service Offer
  1. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Truncating mutations in TAF4B and ZMYND15 causing recessive azoospermia."J. Med. Genet. 51:239-244(2014) [PubMed] [Europe PMC] [Abstract]