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EPS8 Like Protein 3 (EPS8L3)

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EPS8R3; Epidermal Growth Factor Receptor Kinase Substrate 8-Like Protein 3; Epidermal growth factor receptor pathway substrate 8-related protein 3

EPS8 Like Protein 3 (EPS8L3)
CCC Q948
HGNC 21297
MGI 2139743
PubMed 23099647
RGD 1308310
UniProt Q8TE67
Wiki EPS8L3
EPS8L3 encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.
EPS8 codes for a protein essential in Ras to Rac signaling leading to actin remodeling. Three genes highly homologous to EPS8 were discovered, thereby defining a novel gene family. The mouse fragments were manually assembled, and the organization of both human and mouse genes was reconstructed. The gene structures in Celera annotations of the human and mouse genomes were compared to outline correspondences and divergences.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EPS8 Like Protein 3 (EPS8L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EPS8 Like Protein 3 (EPS8L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for EPS8 Like Protein 3 (EPS8L3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EPS8 Like Protein 3 (EPS8L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EPS8 Like Protein 3 (EPS8L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for EPS8 Like Protein 3 (EPS8L3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EPS8 Like Protein 3 (EPS8L3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EPS8 Like Protein 3 (EPS8L3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EPS8 Like Protein 3 (EPS8L3) CLIA Kit Customized Service Offer
n/a ELISA Kit for EPS8 Like Protein 3 (EPS8L3) ELISA Kit Customized Service Offer
  1. "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure."Genomics 81:234-244(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway."Mol. Biol. Cell 15:91-98(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening."BMC Immunol. 10:53-53(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Solution structure of the SH3 domain of human hypothetical protein FLJ21522."Submitted (JAN-2006) to the PDB data bank