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Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK)

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Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK)
CCC R009
HGNC 21964
MGI 1921604
UniProt Q96M69
A point mutation was identified in exon 14 of the Leucine-rich Repeats and Guanylate Kinase domain containing () gene, which introduces a pre-mature stop codon into the Lrguk coding sequence.
The function of the LRGUK protein is currently unknown. However preliminary expression and phenotype analysis suggests that Lrguk may have a role in spermiogenesis. The deduced LRGUK protein contains several potentially important domains including a Guanylate Kinase-like (GK) domain and a number of leucine-rich repeats. The GK-like domain has some homology to guanylate kinase, a metabolic enzyme involved in purine nucleotide metabolism. Studies are currently underway to determine whether the LRGUK protein possesses guanylate kinase enzyme activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeats And Guanylate Kinase Domain Containing Protein (LRGUK) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]