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Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1)

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Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1)
CCC R025
HGNC 22223
MGI 1914734
RGD 1307401
UniProt Q7L9B9
Wiki EEPD1
Endonuclease/Exonuclease/phosphatase family is a structural domain found in the large family of proteins including magnesium dependent endonucleases and many phosphatases involved in intracellular signaling.
Anovel protein that mediates etoposide reistance, termed EEPD1. it co-localizes with gamma-H2Ax to sites of DNA damage generated by etoposide.EEPD1 is cytoplasmic but then translocates to the nucleus after etoposide DNA damage, where it localizes to the chromatin at damaged sites.It has a conserved nuclease domain,A nuclease in these assays, perhaps cleaving off the etopside-Topo IIa complex from the ends of the damaged DNA

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Endonuclease/Exonuclease/Phosphatase Family Domain Containing Protein 1 (EEPD1) ELISA Kit Customized Service Offer
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  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]