Solute Carrier Family 10, Member 4 (SLC10A4)
[Edit]Sodium/Bile Acid Cotransporter 4; Na(+)/bile acid cotransporter 4
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Northern analysis revealed that mRNA is ubiquitously expressed in human tissues with the highest levels of mRNA expression in brain, placenta, and liver. In SLC10A4 -transfected CHO cells, immunoblotting analysis and immunofluorescence staining demonstrated a 49-kDa protein that is expressed at the plasma membrane and intracellular compartments. Functional analysis of SLC10A4 showed no significant taurocholate uptake in the presence of sodium when compared to untransfected CHO cells.
This protein has no capacity to transport taurocholate relative to SLC10A1 ; however, given its ubiquitous tissue distribution, it may play a more active role in transporting other endogenous organic anions.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Solute Carrier Family 10, Member 4 (SLC10A4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Solute Carrier Family 10, Member 4 (SLC10A4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Solute Carrier Family 10, Member 4 (SLC10A4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Solute Carrier Family 10, Member 4 (SLC10A4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Solute Carrier Family 10, Member 4 (SLC10A4) | ELISA Kit Customized Service Offer |
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Cloning and molecular characterization of the orphan carrier protein Slc10a4: expression in cholinergic neurons of the rat central nervous system."Neuroscience 152:990-1005(2008) [PubMed] [Europe PMC] [Abstract]
- "SLC10A4 is a protease-activated transporter that transports bile acids."J. Biochem. 154:93-101(2013) [PubMed] [Europe PMC] [Abstract]