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PHD Finger Protein 13 (PHF13)

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p-Tau; SPOC1; Survival time-associated PHD finger protein in ovarian cancer 1

PHD Finger Protein 13 (PHF13)
CCC R049
HGNC 22983
MGI 2446217
RGD 1308145
UniProt Q86YI8
PHF13 is a novel PHD-containing protein. It is a tightly regulated chromatin-associated protein capable of modulating chromatin structure and important for proper mitotic chromosome condensation and cell division.
The crystal structure human PHF13(232-281) is shown as two antiparallel beta sheets in the core of PHD finger, and two short alpha strands swing at one side of the beta sheets. Similar to other PHD modules, PHF2 PHD finger covers two Zinc finger motifs: residue His257 coordinates one zinc atom with Cys235,Cys237, and Cys260; Cys249 form the second zinc finger motif with C-252 and C-274 and C-277. PHF13 has been tested for association to a disease and proposed to participate in a process. Proteins are expected to have molecular functions and to localize in nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PHD Finger Protein 13 (PHF13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PHD Finger Protein 13 (PHF13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PHD Finger Protein 13 (PHF13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PHD Finger Protein 13 (PHF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for PHD Finger Protein 13 (PHF13) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PHD Finger Protein 13 (PHF13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PHD Finger Protein 13 (PHF13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PHD Finger Protein 13 (PHF13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PHD Finger Protein 13 (PHF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for PHD Finger Protein 13 (PHF13) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PHD Finger Protein 13 (PHF13) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PHD Finger Protein 13 (PHF13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PHD Finger Protein 13 (PHF13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PHD Finger Protein 13 (PHF13) CLIA Kit Customized Service Offer
n/a ELISA Kit for PHD Finger Protein 13 (PHF13) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation."J. Cell Sci. 122:2946-2956(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Crystal structure of PHF13 in complex with tri-methylated histone H3K4."Submitted (SEP-2010) to the PDB data bank