Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1)
[Edit]DUSP27; FMDSP; Dual specificity phosphatase DUPD1
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Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dual Specificity Phosphatase And Pro-Isomerase Domain Containing Protein 1 (DUPD1) | ELISA Kit Customized Service Offer |
- "Identification and characterization of DUSP27, a novel dual-specific protein phosphatase."FEBS Lett. 581:2527-2533(2007) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Structure of human dual-specificity phosphatase 27 at 2.38 A resolution."Acta Crystallogr. D 67:471-479(2011) [PubMed] [Europe PMC] [Abstract]