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Formin Like Protein 3 (FMNL3)

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WBP3; FHOD3; WW domain-binding protein 3; Formin homology 2 domain-containing protein 3

Formin Like Protein 3 (FMNL3)
CCC R134
HGNC 23698
MGI 109569
PubMed 23222643
UniProt Q8IVF7
FMNL3 contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described.
FMNL is a 5'-truncated partial cDNA encoding a Formin-homology protein related to DAAM1, DAAM2, DIAPH1 and DIAPH2.FMNL1 mRNA was expressed in natural killer cells, Burkitt lymphoma, pancreatic cancer, prostate cancer, and lung large cell carcinoma, FMNL2 mRNA in several normal tissues, diffuse-type gastric cancer, breast cancer, chondrosarcoma, melanoma, and glioblastoma, and FMNL3 mRNA in gastric cancer. FMNL1, FMNL2 and FMNL3 might be implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Formin Like Protein 3 (FMNL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Formin Like Protein 3 (FMNL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Formin Like Protein 3 (FMNL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Formin Like Protein 3 (FMNL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Formin Like Protein 3 (FMNL3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Formin Like Protein 3 (FMNL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Formin Like Protein 3 (FMNL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Formin Like Protein 3 (FMNL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Formin Like Protein 3 (FMNL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Formin Like Protein 3 (FMNL3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico."Int. J. Oncol. 22:1161-1168(2003) [PubMed] [Europe PMC] [Abstract]
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  7. "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."BMC Biol. 9:54-54(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Bi-modal regulation of a formin by srGAP2."J. Biol. Chem. 286:6577-6586(2011) [PubMed] [Europe PMC] [Abstract]