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CBP80/CBP20 Dependent Translation Initiation Factor (CTIF)

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KIAA0427

CBP80/CBP20 Dependent Translation Initiation Factor (CTIF)
CCC R163
HGNC 23925
MGI 2685518
RGD 1311887
UniProt O43310
CTIF is a component of the CBP80 (NCBP1)/CBP20 (NCBP2) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G), and steady-state translation of the mRNAs resumes in the cytoplasm. The deduced 598-amino acid protein had an apparent molecular mass of 78 kD by SDS-PAGE. RT-PCR detected KIAA0427 expression in all adult human tissues examined, with highest expression in brain, followed by lung, kidney, prostate, testis, and ovary.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) CLIA Kit Customized Service Offer
n/a ELISA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) CLIA Kit Customized Service Offer
n/a ELISA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) CLIA Kit Customized Service Offer
n/a ELISA Kit for CBP80/CBP20 Dependent Translation Initiation Factor (CTIF) ELISA Kit Customized Service Offer
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