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Apolipoprotein O Like Protein (APOOL)

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CXorf33, FAM121A; Family With Sequence Similarity 121A; MICOS complex subunit MIC27

Apolipoprotein O Like Protein (APOOL)
CCC R166
HGNC 24009
MGI 1915367
PubMed 23704930
RGD 1549725
UniProt Q6UXV4
Apolipoproteins are a homologous gene family that is mostly expressed in liver tissue . They are the major components of HDLs and LDLs so they are responsible for transporting fatty acids and cholesterol in the blood circulation and they bind receptors, which control the intake of the lipoproteins. Many apolipoprotein gene family members are located in gene clusters on different chromosomes. There are eight well-characterized apolipoproteins: APOA1, APOA2, APOA5, APOB, APOC1, APOC2, APOC3, and APOE. Some of them are already identified as PPAR target genes. Not so well known apolipoproteins are: APOA, APOC4, APOD, APOH, APOL, APOM, APOO and APOOL. APOO and APOOL are expressed only in HepG2 cell line. APOO gene expression is not affected by PPAR ligands. is induced after 4 and 6 h with PPARα ligand.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apolipoprotein O Like Protein (APOOL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Apolipoprotein O Like Protein (APOOL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apolipoprotein O Like Protein (APOOL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apolipoprotein O Like Protein (APOOL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein O Like Protein (APOOL) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apolipoprotein O Like Protein (APOOL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Apolipoprotein O Like Protein (APOOL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apolipoprotein O Like Protein (APOOL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apolipoprotein O Like Protein (APOOL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein O Like Protein (APOOL) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Apolipoprotein O Like Protein (APOOL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Apolipoprotein O Like Protein (APOOL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Apolipoprotein O Like Protein (APOOL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Apolipoprotein O Like Protein (APOOL) CLIA Kit Customized Service Offer
n/a ELISA Kit for Apolipoprotein O Like Protein (APOOL) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  5. "APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria."PLoS ONE 8:E63683-E63683(2013) [PubMed] [Europe PMC] [Abstract]
  6. "Uniform nomenclature for the mitochondrial contact site and cristae organizing system." J. Cell Biol. 204:1083-1086(2014) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]