Torsin A Interacting Protein 2 (TOR1AIP2)
[Edit]LULL1; NET9; IFRG15; Lumenal domain-like LAP1; Torsin-1A-interacting protein 2
TorsinA is the causative protein in early onset torsion dystonia, also known as DYT1 dystonia or Oppenheim’s Disease. The disease is characterized by severe and generalized abnormalities in motor control that typically begin during childhood. A candidate-based screen to determine whether any of a set of known NE proteins associate with torsinA uncovered an interaction with the inner nuclear membrane protein LAP1 (also known as TOR1AIP1) and a related protein in the ER, LULL1 (also known as TOR1AIP2 or NET9).
The related transmembrane proteins and LAP1 are prominent binding partners for torsinA in U2OS cells.Impaired interaction of torsinA with LULL1 and/or LAP1 may thus contribute to the development of dystonia.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPR170Hu01 | Recombinant Torsin A Interacting Protein 2 (TOR1AIP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAR170Hu01 | Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2) | WB; IHC; ICC; IP. |
LAR170Hu81 | FITC-Linked Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2) | WB; IHC; ICC; IF. | |
Assay Kits | n/a | CLIA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPR170Mu01 | Recombinant Torsin A Interacting Protein 2 (TOR1AIP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAR170Mu01 | Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Torsin A Interacting Protein 2 (TOR1AIP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Torsin A Interacting Protein 2 (TOR1AIP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Torsin A Interacting Protein 2 (TOR1AIP2) | ELISA Kit Customized Service Offer |
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