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DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B)

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CSP-Beta; Cysteine string protein beta

DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B)
CCC R196
HGNC 24138
MGI 1913576
RGD 1562486
UniProt Q9UF47
The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. They are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. (DnaJ homolog subfamily C member 5B), also designated β-cysteine string protein (β-CSP), is a 199 amino acid protein that contains one J domain and plays an important role in exocytosis. DnaJC5B is expressed in testis where it is tightly bound to lipid membranes. The palmitoylation level of DnaJC5B is thought to correlate with its targeting to specific membranes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) CLIA Kit Customized Service Offer
n/a ELISA Kit for DnaJ/HSP40 Homolog Subfamily C, Member 5B (DNAJC5B) ELISA Kit Customized Service Offer
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Cysteine-string protein isoform beta (Cspbeta) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal beta-cells."Biochim. Biophys. Acta 1773:109-119(2007) [PubMed] [Europe PMC] [Abstract]