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Non SMC Condensin II Complex Subunit D2 (NCAPD2)

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CNAP1; hCAP-D2; CAP-D2; Chromosome Condensation Related SMC Associated Protein 1; Condensin complex subunit 1; XCAP-D2 homolog

Non SMC Condensin II Complex Subunit D2 (NCAPD2)
CCC R221
HGNC 24305
MGI 1915548
PubMed 10958694
RGD 1562596
UniProt Q15021
Wiki NCAPD2
CNAP1 associates with mitotic chromosomes and is homologous to Xenopus condensin component XCAP-D2, indicating the presence of a condensin complex in human cells. Chromosome association of human condensin is mitosis specific, and the majority of condensin dissociates from chromosomes and is sequestered in the cytoplasm throughout interphase. During late G(2)/early prophase, the larger nuclear condensin foci colocalize with phosphorylated histone H3 clusters on partially condensed regions of chromosomes. Mitosis-specific function of human condensin may be regulated by cell cycle-specific subcellular localization of the complex, and the nuclear condensin that associates with interphase chromosomes is involved in the reinitiation of mitotic chromosome condensation in conjunction with phosphorylation of histone H3.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Non SMC Condensin II Complex Subunit D2 (NCAPD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Non SMC Condensin II Complex Subunit D2 (NCAPD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Non SMC Condensin II Complex Subunit D2 (NCAPD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Non SMC Condensin II Complex Subunit D2 (NCAPD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Non SMC Condensin II Complex Subunit D2 (NCAPD2) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 2:167-174(1995) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation."Mol. Cell. Biol. 20:6996-7006(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Chromosome condensation by a human condensin complex in Xenopus egg extracts."J. Biol. Chem. 276:5417-5420(2001) [PubMed] [Europe PMC] [Abstract]
  6. "Identification of a chromosome-targeting domain in the human condensin subunit CNAP1/hCAP-D2/Eg7."Mol. Cell. Biol. 22:5769-5781(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  9. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  10. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  12. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  13. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]