Desumoylating Isopeptidase 1 (DESI1)
[Edit]FAM152B; PPPDE2; Family With Sequence Similarity 152, Member B; PPPDE Peptidase Domain Containing Protein 2
Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility
locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The gene product has been provisionally designated PPPDE2 pending further characterization.
locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The gene product has been provisionally designated PPPDE2 pending further characterization.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Desumoylating Isopeptidase 1 (DESI1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Desumoylating Isopeptidase 1 (DESI1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Desumoylating Isopeptidase 1 (DESI1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Desumoylating Isopeptidase 1 (DESI1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Desumoylating Isopeptidase 1 (DESI1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Desumoylating Isopeptidase 1 (DESI1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Desumoylating Isopeptidase 1 (DESI1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Desumoylating Isopeptidase 1 (DESI1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Desumoylating Isopeptidase 1 (DESI1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Desumoylating Isopeptidase 1 (DESI1) | ELISA Kit Customized Service Offer |
- "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "Structure of human PPPDE1."Submitted (FEB-2009) to the PDB data bank