Neuroblastoma Breakpoint Family, Member 14 (NBPF14)

NBPF14 belongs to the NBPF family. encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.Expressed in spleen and fetal liver.

The NBPF genes have a repetitive structure with high intragenic and intergenic sequence similarity in both coding and noncoding regions. These similarities might expose these genomic regions to illegitimate recombination, resulting in structural variation in the NBPF genes. In silico analysis combined with the isolation of multiple full-length cDNA clones showed that several members of this gene family are abundantly expressed in a large variety of tissues and cell lines.