Seasonal allergic rhinitis (SAR) is a common allergic disorder characterized by episodes of sneezing, rhinorrhea, and swelling of the nasal mucosa. Although the pathogenesis of SAR remains unclear, there does appear to be a genetic predisposition to development of SAR. The haplotype-based haplotype relative risk approach revealed that SNPs in SDA1 domain containing 1; chemokine, CXC motif, ligand (CXCL)-9; CXCL10; and CXCL11 were associated with SAR. These SNPs made up a haplotype block, and the most common haplotype of this block was transmitted preferentially to affected offspring.genetic variations in a haplotype block spanning the SDA1 domain containing 1(SDAD1) and CXC chemokine genes on 4q21 may contribute to development of SAR in the Japanese population.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SDA1 Domain Containing Protein 1 (SDAD1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SDA1 Domain Containing Protein 1 (SDAD1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SDA1 Domain Containing Protein 1 (SDAD1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SDA1 Domain Containing Protein 1 (SDAD1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SDA1 Domain Containing Protein 1 (SDAD1) | ELISA Kit Customized Service Offer |
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Directed proteomic analysis of the human nucleolus."Curr. Biol. 12:1-11(2002) [PubMed] [Europe PMC] [Abstract]
- "Expression and localization studies of hSDA, the human ortholog of the yeast SDA1 gene."Cell Cycle 3:486-490(2004) [PubMed] [Europe PMC] [Abstract]
- "Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind."Genomics 85:92-105(2005) [PubMed] [Europe PMC] [Abstract]
- "Association of a haplotype block spanning SDAD1 gene and CXC chemokine genes with allergic rhinitis."J. Allergy Clin. Immunol. 115:548-554(2005) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
- "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]