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SET Domain Containing Protein 5 (SETD5)

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SET Domain Containing Protein 5 (SETD5)
CCC R443
HGNC 25566
MGI 1920145
PubMed 24680889
RGD 1310433
UniProt Q9C0A6
Wiki SETD5
SETD5contains 1 SET domain. Proteins bearing the widely distributed SET domain have been shown to methylate lysine residues in histones and other proteins. The structures reveal novel folds for several new domains, including SET, and provide early insights into mechanisms of catalysis and molecular recognition in this family of enzymes. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1, and angiogenesis suppressor SEMA3B.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 5 (SETD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 5 (SETD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 5 (SETD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 5 (SETD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 5 (SETD5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 5 (SETD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 5 (SETD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 5 (SETD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 5 (SETD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 5 (SETD5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SET Domain Containing Protein 5 (SETD5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SET Domain Containing Protein 5 (SETD5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SET Domain Containing Protein 5 (SETD5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SET Domain Containing Protein 5 (SETD5) CLIA Kit Customized Service Offer
n/a ELISA Kit for SET Domain Containing Protein 5 (SETD5) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "De novo loss-of-function mutations in SETD5, encoding a methyltransferase in a 3p25 microdeletion syndrome critical region, cause intellectual disability."Am. J. Hum. Genet. 94:618-624(2014) [PubMed] [Europe PMC] [Abstract]