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WD Repeat Containing Domain Protein 33 (WDR33)

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WDC146; NET14; WD repeat-containing protein WDC146; pre-mRNA 3' end processing protein WDR33

WD Repeat Containing Domain Protein 33 (WDR33)
CCC R459
HGNC 25651
MGI 1921570
PubMed 24145821
RGD 1309230
UniProt Q9C0J8
Wiki WDR33
WDR33 encodes a member of the WD repeat protein family. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
The human WDC146 gene had 22 exons spanning over 105 kb, and these exons were distributed in three islands intervened by two long introns of around 40 kb. A minimum promoter region was identified within a 0.5 kb 5'-upstream region of exon 1. WDC146 mRNA was most highly expressed in human testis on Northern blot analysis. In mouse tissues, the highest expression was also observed in testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD Repeat Containing Domain Protein 33 (WDR33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD Repeat Containing Domain Protein 33 (WDR33) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD Repeat Containing Domain Protein 33 (WDR33) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD Repeat Containing Domain Protein 33 (WDR33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD Repeat Containing Domain Protein 33 (WDR33) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD Repeat Containing Domain Protein 33 (WDR33) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD Repeat Containing Domain Protein 33 (WDR33) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD Repeat Containing Domain Protein 33 (WDR33) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD Repeat Containing Domain Protein 33 (WDR33) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD Repeat Containing Domain Protein 33 (WDR33) ELISA Kit Customized Service Offer
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  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Molecular architecture of the human pre-mRNA 3' processing complex."Mol. Cell 33:365-376(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]