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LAS1 Like Protein (LAS1L)

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Ribosomal biogenesis protein LAS1L

LAS1 Like Protein (LAS1L)
CCC R471
HGNC 25726
MGI 1923380
PubMed 20647540
RGD 1565755
UniProt Q9Y4W2
Wiki LAS1L
Ribosome biogenesis is a highly regulated process ensuring that cell growth is coordinated with cell proliferation. The formation of eukaryotic ribosomes is a multistep process initiated by the transcription and processing of rRNA in the nucleolus. several preribosomal particles, which transiently associate with numerous nonribosomal factors before mature 60S and 40S subunits are formed and exported in the cytoplasm, are generated. Depletion of Las1L causes inhibition of cell proliferation characterized by a G1 arrest dependent on the tumor suppressor p53. Las1L is crucial for ribosome biogenesis and that depletion of Las1L leads to inhibition of rRNA processing and failure to synthesize the mature 28S rRNA. Las1L is essential for cell proliferation and biogenesis of the 60S ribosomal subunit.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant LAS1 Like Protein (LAS1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to LAS1 Like Protein (LAS1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to LAS1 Like Protein (LAS1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for LAS1 Like Protein (LAS1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for LAS1 Like Protein (LAS1L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant LAS1 Like Protein (LAS1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to LAS1 Like Protein (LAS1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to LAS1 Like Protein (LAS1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for LAS1 Like Protein (LAS1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for LAS1 Like Protein (LAS1L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant LAS1 Like Protein (LAS1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to LAS1 Like Protein (LAS1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to LAS1 Like Protein (LAS1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for LAS1 Like Protein (LAS1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for LAS1 Like Protein (LAS1L) ELISA Kit Customized Service Offer
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