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INO80 Complex Subunit D (INO80D)

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INO80 Complex Subunit D (INO80D)
CCC R527
HGNC 25997
MGI 3027003
PubMed 22276136
RGD 1304808
UniProt Q53TQ3
INO80D belongs to the INO80D family. The mammalian Tip49a and Tip49b proteins belong to an evolutionarily conserved family of AAA+ ATPases. In Saccharomyces cerevisiae, orthologs of Tip49a and Tip49b, called Rvb1 and Rvb2, respectively, are subunits of two distinct ATP-dependent chromatin remodeling complexes, SWR1 and INO80. The mammalian Tip49a and Tip49b proteins are integral subunits of a chromatin remodeling complex bearing striking similarities to the S. cerevisiae SWR1 complex.
Similar to the yeast INO80 complex, the hINO80 complex exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant INO80 Complex Subunit D (INO80D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to INO80 Complex Subunit D (INO80D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to INO80 Complex Subunit D (INO80D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for INO80 Complex Subunit D (INO80D) CLIA Kit Customized Service Offer
n/a ELISA Kit for INO80 Complex Subunit D (INO80D) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant INO80 Complex Subunit D (INO80D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to INO80 Complex Subunit D (INO80D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to INO80 Complex Subunit D (INO80D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for INO80 Complex Subunit D (INO80D) CLIA Kit Customized Service Offer
n/a ELISA Kit for INO80 Complex Subunit D (INO80D) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant INO80 Complex Subunit D (INO80D) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to INO80 Complex Subunit D (INO80D) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to INO80 Complex Subunit D (INO80D) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for INO80 Complex Subunit D (INO80D) CLIA Kit Customized Service Offer
n/a ELISA Kit for INO80 Complex Subunit D (INO80D) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex."J. Biol. Chem. 280:41207-41212(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex."Mol. Cell 31:909-917(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling."J. Biol. Chem. 286:11283-11289(2011) [PubMed] [Europe PMC] [Abstract]