POU Domain Class 5 Transcription Factor 2 (POU5F2)

POU5F2, Belongs to the POU transcription factor family. Class-5 subfamily. POU domain genes constitute a family of transcription factors that exhibit distinct temporal and spatial patterns of expression.

In the brain, the highest expression levels were found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. mPOU is shown to bind to DNA sequences containing the octamer motif and other POU factor target sites. The distinct expression pattern and divergent DNA-binding characteristics indicate that mPOU may regulate a distinct set of genes.