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TMEM154 regulation by known inflammatory mediators suggests that it heavily influences monocyte maturation and inflammatory response regulation. Since inflammation diseases are important contributors to the morbidity in AI/AN communities, particularly children, furthering knowledge of this gene will lead to insights and identification of new therapy targets. TMEM154 controls the monocyte movement, the first cells to enter the joints of children with poly JIA. TMEM154 is blunted in neonatal immune responses and increased in children with poly JIA.
TMEM154 appeared more selectively regulated during IL-4-induced differentiation of monocytes than IFNg. TMEM154 mRNA expressed a pattern distinctly different from undifferentiated cells, TMEM154 was up regulated in THP-1 cells differentiated into macrophages.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 154 (TMEM154) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 154 (TMEM154) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 154 (TMEM154) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 154 (TMEM154) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 154 (TMEM154) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 154 (TMEM154) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 154 (TMEM154) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 154 (TMEM154) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 154 (TMEM154) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 154 (TMEM154) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 154 (TMEM154) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 154 (TMEM154) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 154 (TMEM154) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 154 (TMEM154) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 154 (TMEM154) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]