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Echinoderm Microtubule Associated Protein Like Protein 3 (EML3)

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ELP95; EMAP-3

Echinoderm Microtubule Associated Protein Like Protein 3 (EML3)
CCC R648
HGNC 26666
MGI 2387612
PubMed 18445686
UniProt Q32P44
EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.An important subset of mitotic microtubule-binding proteins localises to the nucleus in interphase and essentially contributes to spindle formation and function after nuclear envelope breakdown.
EML3 colocalises with spindle microtubules throughout all mitotic stages. In interphase, EML3 colocalised with cytoplasmic microtubules and accumulated in interphase nuclei. Using YFP-fusion constructs of EML3, Functional analysis of EML3 using time-lapse fluorescence microscopy and detailed end-point analysis of phenotypes after siRNA knockdown demonstrates an important role for EML3 in correct metaphase chromosome alignment.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Echinoderm Microtubule Associated Protein Like Protein 3 (EML3) ELISA Kit Customized Service Offer
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