Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1)

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Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1)
Two other proteins (AFAP and AFAP1L1) were found to have a significant similarity to XB130 and were compared in detail. After an analysis of these three proteins, it was proposed that they are members of a novel protein family, termed the “AFAP family of signal adaptor proteins”. The objective of the present study was to perform a genome wide search of proteins which are similar to XB130 and AFAP, and to gain systemic knowledge of these proteins for their expression, distribution, and potential functions. Sequence alignment showed that all three of these proteins have approximately 25% identical amino acids and share many conserved functional domains including N-terminal SH2/SH3 binding domains, two consecutive pleckstrin homology domains; however differ in their unique C-terminal regions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actin Filament Associated Protein 1 Like Protein 1 (AFAP1L1) ELISA Kit Customized Service Offer
  1. "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."DNA Res. 10:49-57(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes."Eur. J. Cell Biol. 90:376-389(2011) [PubMed] [Europe PMC] [Abstract]