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TBC1 Domain Containing Kinase (TBCK)

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TBCKL; TBC domain-containing protein kinase-like protein

TBC1 Domain Containing Kinase (TBCK)
CCC R799
HGNC 28261
MGI 2445052
PubMed 23977024
RGD 1307816
UniProt Q8TEA7
TBCK, Belongs to the protein kinase superfamily. This provides a starting point for comprehensive analysis of protein phosphorylation in normal and disease states, as well as a detailed view of the current state of human genome analysis through a focus on one large gene family.
New genes include members of well-studied families as well as previously unidentified families, some of which are conserved in model organisms. Classification and comparison with model organism kinomes identified orthologous groups and highlighted expansions specific to human and other lineages. Chromosomal mapping revealed several small clusters of kinase genes and revealed that 244 kinases map to disease loci or cancer amplicons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Containing Kinase (TBCK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Containing Kinase (TBCK) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Containing Kinase (TBCK) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Containing Kinase (TBCK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Containing Kinase (TBCK) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Containing Kinase (TBCK) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TBC1 Domain Containing Kinase (TBCK) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TBC1 Domain Containing Kinase (TBCK) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TBC1 Domain Containing Kinase (TBCK) CLIA Kit Customized Service Offer
n/a ELISA Kit for TBC1 Domain Containing Kinase (TBCK) ELISA Kit Customized Service Offer
  1. "Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity."Genes Cells 14:41-52(2009) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] and Trachea.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract], Placenta and Prostate.
  5. "The protein kinase complement of the human genome."Science 298:1912-1934(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]