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tRNA Methyltransferase 10 Homolog A (TRMT10A)

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TRM10; RG9MTD2; RNA Guanine-9-Methyltransferase Domain Containing Protein 2

tRNA Methyltransferase 10 Homolog A (TRMT10A)
CCC R823
HGNC 28403
MGI 1920421
PubMed 24204302
RGD 1594565
UniProt Q8TBZ6
Wiki Rg9mtd2
The RNA methyltransferase family of proteins catalyze the transfer of a methyl group from a donor to an RNA acceptor. Via their ability to modify RNA, RNA methyltransferase proteins play an important role in cell growth and signaling pathways and may be involved in tumor development and progression. The RNA (guanine-9-) methyltransferase domain containing proteins (namely RG9MTD1, RG9MTD2 and RG9MTD3) are probable RNA methyltransferases that may play a role in RNA modification. Due to their involvement in RNArelated pathways, the RG9MTD proteins may be associated with methylation events that lead to carcinogenesis. While both RG9MTD1 and exist as one known isoform, RG9MTD3 is expressed as three isoforms produced by alternative splicing events.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 10 Homolog A (TRMT10A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 10 Homolog A (TRMT10A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant tRNA Methyltransferase 10 Homolog A (TRMT10A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to tRNA Methyltransferase 10 Homolog A (TRMT10A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) CLIA Kit Customized Service Offer
n/a ELISA Kit for tRNA Methyltransferase 10 Homolog A (TRMT10A) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans."PLoS Genet. 9:E1003888-E1003888(2013) [PubMed] [Europe PMC] [Abstract]
  4. "TRMT10A dysfunction is associated with abnormalities in glucose homeostasis, short stature and microcephaly."J. Med. Genet. 51:581-586(2014) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]