Members of the leucine-rich repeat family includes LRCH1, LRCH2, LRCH3 and LRCH4. All family members contain one calponin-homology domain and nine leucine-rich repeats. The best characterized leucine-rich repeat family member is LRCH4, which is suggested to be involved in ligand binding in the brain, with expression observed primarily in the hippocampus. As a cell adhesion molecule and signal receptor, LRCH4 may play an important role in maintenance of hippocampus-dependent memories, with defects in the gene possibly contributing to a loss of long-term memory. The gene encoding maps to human chromosome 3, which spans 200 million base pairs and encodes between 1,100 and 1,500 genes. There are three isoforms of LRCH3 that are produced as a result of alternative splicing events.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat And Calponin Homology Domain Containing Protein 3 (LRCH3) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."J. Proteome Res. 7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]