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DIS3 Mitotic Control Homolog Like Protein (DIS3L)

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Dis3L1

DIS3 Mitotic Control Homolog Like Protein (DIS3L)
CCC R872
HGNC 28698
MGI 2143272
PubMed 20531389
RGD 1308959
UniProt Q8TF46
Wiki DIS3L
Dis3L is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the cytoplasm of eukaryotic cells.
DIS3L belongs to the ribonuclease II (RNB) family. Ribonuclease II (RNase II) is a major exoribonuclease that intervenes in all of these fundamental processes; it can act independently or as a component of the exosome, an essential RNA-degrading multiprotein complex. RNase II-like enzymes are found in all three kingdoms of life, but there are no structural data for any of the proteins of this family. RNase R is a close homolog of RNase II, but it can, unlike RNase II, degrade RNA with secondary structures without help of accessory factors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DIS3 Mitotic Control Homolog Like Protein (DIS3L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) CLIA Kit Customized Service Offer
n/a ELISA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DIS3 Mitotic Control Homolog Like Protein (DIS3L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) CLIA Kit Customized Service Offer
n/a ELISA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DIS3 Mitotic Control Homolog Like Protein (DIS3L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DIS3 Mitotic Control Homolog Like Protein (DIS3L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) CLIA Kit Customized Service Offer
n/a ELISA Kit for DIS3 Mitotic Control Homolog Like Protein (DIS3L) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins."DNA Res. 8:319-327(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L."EMBO J. 29:2342-2357(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Dis3-like 1: a novel exoribonuclease associated with the human exosome."EMBO J. 29:2358-2367(2010) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]