Coenzyme Q6 Homolog, Monooxygenase (COQ6)

[Edit]

CGI-10; Coenzyme Q10 monooxygenase 6; Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

Coenzyme Q6 Homolog, Monooxygenase (COQ6)
Coenzyme Q (Q) is a lipid that functions as an electron carrier in the mitochondrial respiratory chain in eukaryotes. Coq6 mutants are unable to grow on nonfermentable carbon sources and do not synthesize Q but instead accumulate the Q biosynthetic intermediate 3-hexaprenyl-4-hydroxybenzoic acid. The Coq6 polypeptide is imported into the mitochondria in a membrane potential-dependent manner. Coq6p is a peripheral membrane protein that localizes to the matrix side of the inner mitochondrial membrane. COQ6 encodes a flavin-dependent monooxygenase required for one or more steps in Q biosynthesis. COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR876Hu01 Recombinant Coenzyme Q6 Homolog, Monooxygenase (COQ6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAR876Hu01 Polyclonal Antibody to Coenzyme Q6 Homolog, Monooxygenase (COQ6) WB; IHC; ICC; IP; FCM
Assay Kits n/a CLIA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Coenzyme Q6 Homolog, Monooxygenase (COQ6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Coenzyme Q6 Homolog, Monooxygenase (COQ6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Coenzyme Q6 Homolog, Monooxygenase (COQ6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPR876Ra01 Recombinant Coenzyme Q6 Homolog, Monooxygenase (COQ6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAR876Ra01 Polyclonal Antibody to Coenzyme Q6 Homolog, Monooxygenase (COQ6) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coenzyme Q6 Homolog, Monooxygenase (COQ6) ELISA Kit Customized Service Offer
  1. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption." J. Clin. Invest. 123:5179-5189(2013) [PubMed] [Europe PMC] [Abstract]
  7. "COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness." J. Clin. Invest. 121:2013-2024(2011) [PubMed] [Europe PMC] [Abstract]