HRF(+) cells showed a selective down-regulation of 11 genes involved in transcription, several of which are implicated in either susceptibility of cells to HIV-1 or the promotion of HIV-1 transcription itself. In the group of the up-regulated genes, three were linked directly to the cellular resistance to HIV-1.
One of the cDNAs placed on the array, representing the hypothetical protein KIAA0117 hybridized only with poly A+ RNA probes derived from HRF(+) cells. The specific up-regulation of two genes, the transcription repressor (CTCF) and hypothetical protein KIAA0117 was confirmed by RT-PCR and Northern blot. The role of KIAA0117 transcript in the resistance to HIV-1 replication needs to be determined.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RNA Binding Motif Protein 34 (RBM34) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RNA Binding Motif Protein 34 (RBM34) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RNA Binding Motif Protein 34 (RBM34) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RNA Binding Motif Protein 34 (RBM34) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RNA Binding Motif Protein 34 (RBM34) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RNA Binding Motif Protein 34 (RBM34) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant RNA Binding Motif Protein 34 (RBM34) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to RNA Binding Motif Protein 34 (RBM34) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for RNA Binding Motif Protein 34 (RBM34) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for RNA Binding Motif Protein 34 (RBM34) | ELISA Kit Customized Service Offer |
- "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 2:37-43(1995) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Functional proteomic analysis of human nucleolus."Mol. Biol. Cell 13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]