Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppeltype DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.
As a member of the krueppel C2H2-type zinc-finger protein family, (zinc-finger protein 516) is a 1,163 amino acid nuclear protein that contains ten C2H2-type zincfingers. The gene encoding ZNF516 maps to human chromosome 18, in a region that is frequently found to be affected in 18q deletion syndrome, a multiple-anomaly mental retardation syndrome that is associated with congenital aural atresia.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Protein 516 (ZNF516) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Protein 516 (ZNF516) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Protein 516 (ZNF516) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Protein 516 (ZNF516) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Protein 516 (ZNF516) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Protein 516 (ZNF516) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger Protein 516 (ZNF516) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger Protein 516 (ZNF516) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger Protein 516 (ZNF516) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger Protein 516 (ZNF516) | ELISA Kit Customized Service Offer |
- "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Replication stress links structural and numerical cancer chromosomal instability." Nature 494:492-496(2013) [PubMed] [Europe PMC] [Abstract]
- "Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat."Mol. Cell 57:235-246(2015) [PubMed] [Europe PMC] [Abstract]