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Kelch Like Protein 18 (KLHL18)

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Kelch Like Protein 18 (KLHL18)
CCC R943
HGNC 29120
MGI 2143315
PubMed 23213400
RGD 1310570
UniProt O94889
Wiki KLHL18
KLHL18 is a 574 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL18 protein contains six kelch repeats, one BACK domain and one BTB (POZ) domain. The BTB domain, also known as the POZ domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL18 that are produced as a result of alternative splicing events.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 18 (KLHL18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 18 (KLHL18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 18 (KLHL18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 18 (KLHL18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 18 (KLHL18) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 18 (KLHL18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 18 (KLHL18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 18 (KLHL18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 18 (KLHL18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 18 (KLHL18) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 18 (KLHL18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 18 (KLHL18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 18 (KLHL18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 18 (KLHL18) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 18 (KLHL18) ELISA Kit Customized Service Offer
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  5. "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract]