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WD And Tetratricopeptide Repeats Protein 1 (WDTC1)

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ADP; DCAF9; Adipose Homolog; DDB1 And CUL4 Associated Factor 9

WD And Tetratricopeptide Repeats Protein 1 (WDTC1)
CCC R955
HGNC 29175
MGI 2685541
PubMed 17767906
RGD 1310362
UniProt Q8N5D0
Wiki WDTC1
WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake. Five WDTC1 single-nucleotide polymorphisms (SNPs) were genotyped in 935 and 1,115 adults of two ethnically diverse US populations. Two WDTC1 SNPs strongly associated with obesity. A white population also exhibited a pattern of association between WDTC1 genotypes and obesity although of a different nature.
Those WDTC1 variants which associated with obesity likely have experienced strong positive selection in human history, when food supply was unpredictable. Given the high frequency of the major alleles in both populations, WDTC1 variation may be an important risk factor contributing to obesity in these populations.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to WD And Tetratricopeptide Repeats Protein 1 (WDTC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for WD And Tetratricopeptide Repeats Protein 1 (WDTC1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery."Nature 443:590-593(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]