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MON2 Homolog (MON2)

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MON2 Homolog (MON2)
CCC R957
HGNC 29177
MGI 1914324
PubMed 22594927
RGD 1308808
UniProt Q7Z3U7
Wiki MON2
Mon2 is distantly related to the guanine nucleotide exchange factors (GEFs) that activate Arf1 on Golgi membranes.Mon2 lacks the Sec7 domain that catalyzes nucleotide exchange on Arf1. Mon2 shares extensive homology with the noncatalytic parts of both the BIG and Golgi brefeldin A resistance factor subfamilies of Arf GEFs and is located to the trans-Golgi. Mon2 forms a complex with Dop1, a large cytoplasmic protein conserved in evolution from humans to protozoa. Deletion of Mon2 results in mislocalization of Dop1 from the Golgi and defects in cycling between endosomes and the Golgi. However, unlike Mon2, Dop1 is essential for yeast viability.Thus, it appears that Dop1 plays a widespread role in membrane organization, and Mon2 acts as a scaffold to recruit the Golgi-localized pool of Dop1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MON2 Homolog (MON2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MON2 Homolog (MON2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MON2 Homolog (MON2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MON2 Homolog (MON2) CLIA Kit Customized Service Offer
n/a ELISA Kit for MON2 Homolog (MON2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MON2 Homolog (MON2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MON2 Homolog (MON2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MON2 Homolog (MON2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MON2 Homolog (MON2) CLIA Kit Customized Service Offer
n/a ELISA Kit for MON2 Homolog (MON2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant MON2 Homolog (MON2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to MON2 Homolog (MON2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to MON2 Homolog (MON2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for MON2 Homolog (MON2) CLIA Kit Customized Service Offer
n/a ELISA Kit for MON2 Homolog (MON2) ELISA Kit Customized Service Offer
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