≡

Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9)

[Edit]

p60TRP; Transcription Regulator of 60 kDa; p60-Transcription-Regulator-Protein

Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9)
CCC R992
HGNC 29353
MGI 1917487
PubMed 20954177
RGD 1303224
UniProt Q6PI77
Active cell death ('apoptosis' or 'programmed cell death') is essential in the development and homeostasis of multicellular organisms and abnormal inhibition of apoptosis is an indicator of cancer and autoimmune diseases, whereas excessive cell death might be implicated in neurodegenerative disorders such as Alzheimer's disease (AD).
p60TRP is a basic helix-loop-helix (bHLH) domain-containing member of a new protein family that interacts with the Ran-binding-protein-5 (RanBP5) and the protein-phosphatase-2A (PP2A). The additional findings of its influence on NNT1 and p48ZnF (new-neurotrophin-1, p48-zinc-finger-protein)-signaling and its down-regulation in the brain of AD subjects point to a possible pivotal role of p60TRP in the control of cellular aging and survival.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Basic Helix Loop Helix Domain Containing Protein B9 (BHLHB9) ELISA Kit Customized Service Offer
  1. "Characterizing the new transcription regulator protein p60TRP."J. Cell. Biochem. 91:1030-1042(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells."Cancer Res. 67:11481-11486(2007) [PubMed] [Europe PMC] [Abstract]